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Blood supply, production of plasma derivatives, research and education, diagnostic products and services are the main activities of the Sanquin Blood Supply Foundation. The Amsterdam-based Division of Diagnostic Services has established a diagnostic service to Dutch medical institutions, including state-of-the-art logistics and data-management. The assays provided are outlined below and are also accessible to the (international) market.
This advanced capacity is also engaged in supporting international multicenter trials in the field of blood and blood-related diseases and disorders.
In addition to the following summary of readily available tests, the specialists of our research department are capable of devising tailor-made tests to meet your specific demands.


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Sanquin's diagnostic tests for plasma components

Serum proteins
  • Levels of (sub) classes of immunoglobulins
  • Complement factors (quantitatively; e.g. C1q, C3, C3d, C4, C5, B)
  • Complement functions (e.g. C50, AP50, C3-nephritic factor)
  • C1 esterase inhibitor
  • Circulating immune complexes
  • (Pre)albumin
  • a-1-antitrypsin
  • a-1-foetoprotein
  • a-1-acid glycoprotein
  • a-2-macroglobulin
  • b-2-microglobulin
  • ceruloplasmin
  • MBL
  • transferrin
    Acute phase proteins
  • CRP
  • SPLA2
  • MBL
  • ferritin

  • Coagulation or complement related proteins
  • TFPI
  • sTF (tissue factor)
  • Various clotting proteases (kallikrein, XIIa, thrombin a.o.) by itself or in complex with inhibitors (C1-inh, a1-AT, a2-M)
  • LAC
  • sCD46
  • sCD55
    Markers of cellular activation
  • Elastase
  • Elastase-a-1-AT complexes
  • Lactoferrin (neutrophils)
  • Granzym A (NK cells)
  • Granzym B (cytotoxic T cells)
  • Nucleosomes
  • sCD16
  • sCD27

  • Plasma protein research at Sanquin
    Our specialists can provide you with more information on these tests and will be happy to discuss with you the development of specific tests for your research:
    Prof. Lucien Aarden, PhD

    Telephone: +31 20 512 34 79
    diagnostic.services@sanquin.nl

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