|
| Home | ● | Contact | ● | Sanquin | ● | News | ● | Jobs | ● | Sitemap | ● |
|
Tetramers home |
| PeliMers |
| FlexMers |
| PeliChange/Screen |
| Custom made |
|
Price lists |
| Background |
| Scientific posters |
| Literature list |
|
Interesting links |
| << Reagents home |
Selected publications from the tetramer facility group: The Netherlands Cancer Institute, Sanquin research at CLB (including the University of Amsterdam and the Academic Medical Centre (AMC) Amsterdam). The use of MHC tetramers for the optimisation of vaccination strategies and dissection of virus-specific T-cell responses. Systemic T-cell expansion during localized viral infection. Eur. J. Immunol. 29:1168-1174 (1999) J.B.A.G. Haanen, M. Toebes, T.A. Cordaro, M.C. Wolkers, A.M. Kruisbeek, T.N.M. Schumacher. Selective expansion of cross-reactive CD8+ memory T-cells by viral variants. J. Exp. Med. 190:1319-1328 (1999) M. Heemskerk, E. Hooiberg, J.J. Ruizendaal, M.C. van der Weide, E. Kueter, A.Q. Bakker, T.N.M. schumacher, H. Spits. CD40 activation in vivo overcomes peptide-induced peripheral cytotoxic T-lymphocyte lymphocyte tolerance and augments anti-tumor vaccine efficacy. Nature Medicine 5: 774-779 (1999). L. Diehl, A. Th. Den Boer, S.P. Schoenberger, E.I.H. van der Voort, T.N.M. Schumacher, C.J.M. Melief, R. Offringa, and R. Toes. Changes in the composition of circulating CD8+ T cell subsets during acute Epstein-Barr virus and human immunodeficiency virus infection in man. J.Infect.Dis. 182:451, 2000. Roos MThL, Van Lier RAW, Hamann D, Knol GJ, Verhoofstad I, van Baarle D, Miedema F, Schellekens PTA. High viral burden in the presence of major HIV-specific CD8+ T cell expansions: evidence for impaired T-cell effector function. Eur.J.Immunol. 31:677, 2001. Kostense S, Ogg GS, Manting EH, Gillespie G, Joling J, Veenhof EZ, Vandenberghe K., van Baarle D, Jurriaans S, Klein MR, Miedema F. van Baarle D, Hovenkamp E, Callan MFC, Wolthers. Dysfunctional Epstein-Barr virus (EBV)-specific CD8+ T lymphocytes and increased EBV load in HIV-1 infected individuals progressing to AIDS-related non-Hodgkin's Lymphoma. Blood 98:146, 2001. KC, Kostense S, Tan L, Niesters HGM, Osterhaus ADME, McMichael A, Miedema F, van Oers MH. Het verloop van HIV-infecties; nieuwe inzichten m.b.t. de immunologie. Pharmaceutisch weekblad 136:5 158-161.2001. Kostense S, van Baarle D, Hazenberg MD, Miedema F. Differential restoration of functional Epstein-Barr virus and Human immunodeficiency virus-1 specific CD8+ T cells during anti-retroviral therapy. Eur J Immunol 32:4. 1080-1089. 2002. Kostense S, Otto SA, Knol GJ, Manting EH, van Oers MH, Miedema F, van Baarle D. Enhanced immunogenicity of HPV E7 fusion proteins in DNA vaccination. Virology 294: 47-59 (2002).N. Michel, W. Osen, L. Gissmann, T.N.M. Schumacher, H. Zentgraf and M. Mueller. Effective post-exposure treatment of retrovirus-induced disease with immunomodulatory DNA containing CpG motifs. J. Virol. 76: 11397-11404 (2002). A.R.M. Olbrich, S. Schimmer, K. Heeg, K. Schepers, T.N.M. Schumacher and U. Dittmer. Lack of Epstein-Barr virus- and HIV-specific CD27- CD8+ T cells is associated with progression to viral disease in HIV-infection. AIDS 16(15): 2001-2011; Oct 2002 Debbie van Baarle; Stefan Kostense; Egbert Hovenkamp; Graham Ogg; Nening Nanlohy; Margaret F. C. Callan; Nicole H. T. M. Dukers; Andrew J. McMichael; Marinus H. J. van Oers; Frank Miedema. Failing immune control as a result of impaired CD8+ T-cell maturation: CD27 might provide a clue. Trends Immunol. 2002 Dec;23(12):586-91. van Baarle D, Kostense S, van Oers MH, Hamann D, Miedema F. HIV-specific CD8+ T cell proliferation is coupled to perforin expression and is maintained in nonprogressors. Nat Immunol. 2002 Nov;3(11):1061-8. Migueles SA, Laborico AC, Shupert WL, Sabbaghian MS, Rabin R, Hallahan CW, Van Baarle D, Kostense S, Miedema F, McLaughlin M, Ehler L, Metcalf J, Liu S, Connors M. Persistent numbers of tetramer+ CD8(+) T cells, but loss of interferon-gamma+ HIV-specific T cells during progression to AIDS. Blood. 2002 Apr 1;99(7):2505-11. Kostense S, Vandenberghe K, Joling J, Van Baarle D, Nanlohy N, Manting E, Miedema F. Single-cell perforin and granzyme expression reveals the anatomical localization of effector CD8+ T cells in influenza virus-infected mice. Proc. Natl. Acad. Sci. USA 100: 2657-2662 (2003). B.J. Johnson, E.O. Costelloe, D.R. Fitzpatrick, J.B.A.G. Haanen, T.N.M. Schumacher, L.E. Brown, and A. Kelso. Impaired recovery of Epstein-Barr virus (EBV)--specific CD8+ T lymphocytes after partially T-depleted allogeneic stem cell transplantation may identify patients at very high risk for progressive EBV reactivation and lymphoproliferative disease. Blood. 2003 Jun 1;101(11):4290-7. Meij P, van Esser JW, Niesters HG, van Baarle D, Miedema F, Blake N, Rickinson AB, Leiner I, Pamer E, Lowenberg B, Cornelissen JJ, Gratama JW.
The use of MHC tetramers for the detection of antigen-specific T cells in tissue sections Tracing and characterization of the low-avidity self-specific T cell repertoire. Eur. J. Immunol. 30: 1458-1468 (2000). K.E. de Visser, D. Kioussis, T.A. Cordaro, J.B.A.G, Haanen, T.N.M. Schumacher, and A.M. Kruisbeek. In situ detection of virus and tumor-specific T cell immunity. Nature Medicine 6:1056-1060 (2000). J.B.A.G. Haanen, M. v. Oijen, F. Tirion, A.M. Kruisbeek, L. Oomen, F. Vyth-Dreese, and T.N.M. Schumacher. In situ dissection of Graft-versus-Host Disease and Graft-versus-Leukemia effects by minor Histocompatibility antigen specific cytotoxic T cells. Nature Medicine 8: 410-414 (2002). A.M. Dickinson, X.N. Wang, L. Sviland, F. Vyth-Dreese, G.H. Jackson, T.N.M. Schumacher, J.B.A.G. Haanen, T. Mutis and E. Goulmy.
The use of MHC tetramers for the optimisation of immunotherapy protocols. Changing T cell specificity by retroviral TCR display. Proc Natl. Acad. Sci. USA 97: 14578-14583 (2000). H.W.H.G. Kessels, M. v.d. Boom, H. Spits, E. Hooijberg, and T.N.M. Schumacher. CDR3 biases in the naïve TCR repertoire alter the cytotoxic T lymphocyte response to an immunodominant determinant of HSV-1. Immunity 12: 547-556 (2000). M.E. Wallace, S.C. Cose, T.N. Schumacher, M. Bryden, R.M. Coles, W.R. Heath, and F.R. Carbone. CD27 is required for generation and long-term maintenance of T cell immunity. Nature Immunology. 1: 433-440 (2000). J. Hendriks, L.A. Gravestein, K. Tesselaar, R.A.W. van Lier, T.N.M. Schumacher and J. Borst. Differentiation of cytomegalovirus-specific CD8+ T cells in healthy and immunosuppressed virus carriers. Blood 98: 754-761 (2001). L.E. Gamadia, R.J. Rentenaar, P.A. Baars, E.B.M. Remmerswaal, S. Surachno, J.F.L. Weel, M. Toebes, T.N.M. Schumacher, I.J.M. ten Berge and R.A.W. van Lier. Inhibition of auto-reactive cytotoxic T lymphocytes through CTLA-4 and CD4+ CD25+ T cells constitute distinct regulatory mechanisms. J. Exp. Med. 194: 823-832 (2001). R.P.M. Sutmuller, L.M. van Duivenvoorde, A. van Elsas, T.N.M. Schumacher, J.P. Allison, R.E.M. Toes, R. Offringa and C.J.M. Melief. Redundancy of direct priming and cross-priming in tumor-specific CD8+ T cell responses. J. Immunol. 167: 3577-3584 (2001). M.C. Wolkers, G. Stoetter, F.A. Vyth-Dreese, and T.N.M. Schumacher. Immunotherapy through TCR gene transfer. Nature Immunology. 2: 957-961 (2001). H.W.H.G. Kessels, M.C. Wolkers, M. v.d. Boom, M. van der Valk, and T.N.M. Schumacher. Can the low avidity self-specific T cell repertoire be exploited for tumor rejection? J Immunol. 168:651-660 (2002). T.A. Cordaro, K.E. de Visser, F.H. Tirion, T.N.M. Schumacher and A.M. Kruisbeek. Ex vivo and in situ tetramer analysis of CTL responses to tumors. In Tumor antigens recognized by T cells and antibodies, Harwood publishers. In press (2002). T.N.M. Schumacher and J.B.A.G. Haanen.
MHC class II tetramers | |