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Blood products, such as erythrocytes, thrombocytes and fresh frozen plasma, are prepared and delivered by the Sanquin Blood Banks within the framework of the Blood Supply Act (Dutch acronym, Wibv). Medicinal products prepared from human plasma fall under the Medicines Act (Dutch acronym, Wog) and are delivered by Sanquin Plasma Products.
This Index part 1 contains the ‘Information for Users’ from the products that Sanquin delivers in the context of the Wibv. The products are prepared in the blood banks in conformity with the Sanquin Guidelines for Blood Products, with due consideration given to the other Sanquin Guidelines. The goal of these Guidelines is to obtain very high quality blood products of a nationally uniform nature.

In May 2001 the Minister of Health, Welfare and Sport decided that only cellular blood products (from which the leukocytes have been removed) may be delivered as from 1 January 2002. This policy is indicated by the term general leukocyte depletion.

Prior to the introduction of general leukocyte depletion, leukocytes were removed from cellular blood products in order to prevent primary immunisation by HLA-antigens, fever reactions in patients with antibodies against leukocytes, transfer of cytomegalovirus, and viral reactivation by the recipient.


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